Dangers of banning spice and the synthetic cannabinoid agonists.
نویسنده
چکیده
منابع مشابه
Cannabinoids in health and disease
Cannabis sativa L. preparations have been used in medicine for millenia. However, concern over the dangers of abuse led to the banning of the medicinal use of marijuana in most countries in the 1930s. Only recently, marijuana and individual natural and synthetic cannabinoid receptor agonists and antagonists, as well as chemically related compounds, whose mechanism of action is still obscure, ha...
متن کاملCP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists.
'Spice' is an herbal blend that has been reported to produce cannabis-like effects when smoked and is marketed as an alternative to marijuana. Synthetic additives have been identified in numerous 'Spice' preparations from different sources. Common among many of the preparations were the compounds JWH018 and a dimethyloctyl variant of CP47,497 (CP47,497-C8) and, more recently JWH073. The synapti...
متن کاملSynthetic cannabinoids in herbal products
Background The recent appearance of synthetic cannabinoids in herbal products ('Spice'), easily available over the internet, has brought to the attention of the international community, the need for sharing of information and greater awareness of this phenomenon. This report was prepared pursuant to the Commission on Narcotic Drugs Resolution 53/11 (Para 6: Requests the United Nations Office on...
متن کاملSynthetic Cannabinoid and Synthetic Cocaine Use during Pregnancy in a Soldier
Synthetic cannabinoid (spice) and synthetic cocaine (bath salts) are relatively new designer drugs of abuse. To date, there have been few reports in the medical literature documenting their use during pregnancy. A 22 year-old gravid woman at 32 weeks gestation presented with suicidal ideation and agitation that required restraints and admission to the psychiatric ward. The woman had a long hist...
متن کامل"Spice" and "K2" herbal highs: a case series and systematic review of the clinical effects and biopsychosocial implications of synthetic cannabinoid use in humans.
Cannabis, the most commonly used illicit substance, exerts its primary psychoactive effect via delta-9 tetrahydrocannabinol (Δ(9) -THC) agonism of cannabinoid receptor type 1 (CB1). Some users develop a cannabis use disorder and physical dependence manifested by withdrawal symptoms during abstinence. Hence, there is growing public health concern about increasing use of a new generation of synth...
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عنوان ژورنال:
- Addiction
دوره 105 2 شماره
صفحات -
تاریخ انتشار 2010